Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2011
Author(s): Dong, Lan-feng, Jameson, Victoria J.A., Tilly, David Patrice, Prochazka, Lubomir, Rohlena, Jakub, Valis, Karel, Truksa, Jaroslav, Zobalova, Renata, Mahdavian, Elahe, Kluckova, Katarina, Stantic, Marina, Stursa, Jan, Freeman, Ruth, Witting, Paul K., Norberg, Erik, Goodwin, Jacob, Salvatore, Brian A., Novotna, Jana, Turanek, Jaroslav, Ledvina, Miroslav, Hozak, Pavel, Zhivotovsky, Boris, Coster, Mark J., Ralph, Stephen John, Smith, Robin A.J., Neuzil, Jiri

Hippo/Mst1 Stimulates Transcription of the Proapoptotic Mediator NOXA in a FoxO1-Dependent Manner
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2011
Author(s): Valis, Karel, Prochazka, Lubomir, Boura, Evzen, Chladova, Jaromira, Obsil, Tomas, Rohlena, Jakub, Truksa, Jaroslav, Dong, Lan-feng, Ralph, Stephen John, Neuzil, Jiri

α-Tocopheryl succinate causes mitochondrial permeabilization by preferential formation of Bak channels
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2010
Author(s): Prochazka, Lubomir, Dong, Lan-feng, Valis, Karel, Freeman, Ruth, Ralph, Stephen John, Turanek, Jaroslav, Neuzil, Jiri

Suppression of Tumor Growth In vivo by the Mitocan α-tocopheryl Succinate Requires Respiratory Complex II
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2009
Author(s): Dong, Lan-feng, Freeman, Ruth, Liu, Ji, Zobalova, Renata, Marin-Hernandez, Alvaro, Stantic, Marina, Rohlena, Jakub, Valis, Karel, Rodriguez-Enriquez, Sara, Butcher, Bevan, Goodwin, Jacob, Brunk, Ulf T., Witting, Paul K., Moreno-Sanchez, Rafael, Scheffler, Immo E., Ralph, Stephen John, Neuzil, Jiri