Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial: Complex II
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2011
Author(s): Dong, Lan-feng, Jameson, Victoria J. A., Tilly, David Patrice, Cerny, Jiri, Mahdavian, Elahe, Marín-Hernandez, Alvaro, Hernandez-Esquivel, Luz, Rodríguez-Enríquez, Sara, Stursa, Jan, Witting, Paul K., Stantic, Bela, Rohlena, Jakub, Truksa, Jaroslav, Kluckova, Katarina, Dyason, Jeffrey Clifford, Ledvina, Miroslav, Salvatore, Brian A., Moreno-Sanchez, Rafael, Coster, Mark J., Ralph, Stephen John, Smith, Robin A. J., Neuzil, Jiri

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2011
Author(s): Dong, Lan-feng, Jameson, Victoria J.A., Tilly, David Patrice, Prochazka, Lubomir, Rohlena, Jakub, Valis, Karel, Truksa, Jaroslav, Zobalova, Renata, Mahdavian, Elahe, Kluckova, Katarina, Stantic, Marina, Stursa, Jan, Freeman, Ruth, Witting, Paul K., Norberg, Erik, Goodwin, Jacob, Salvatore, Brian A., Novotna, Jana, Turanek, Jaroslav, Ledvina, Miroslav, Hozak, Pavel, Zhivotovsky, Boris, Coster, Mark J., Ralph, Stephen John, Smith, Robin A.J., Neuzil, Jiri

Suppression of Tumor Growth In vivo by the Mitocan α-tocopheryl Succinate Requires Respiratory Complex II
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2009
Author(s): Dong, Lan-feng, Freeman, Ruth, Liu, Ji, Zobalova, Renata, Marin-Hernandez, Alvaro, Stantic, Marina, Rohlena, Jakub, Valis, Karel, Rodriguez-Enriquez, Sara, Butcher, Bevan, Goodwin, Jacob, Brunk, Ulf T., Witting, Paul K., Moreno-Sanchez, Rafael, Scheffler, Immo E., Ralph, Stephen John, Neuzil, Jiri

Endogenous adenosine selectively modulates oxidant stress via the A1 receptor in ischemic hearts
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2009
Author(s): Reichelt, Melissa Elizabeth, Shanu, Ana, Willems, Laura, Witting, Paul K., Ellis, Natasha A., Blackburn, Michael R., Headrick, John Patrick

Mitochondria transmit apoptosis signalling in cardiomyocyte-like cells and isolated hearts exposed to experimental ischemia-reperfusion injury
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2007
Author(s): Neuzil, Jiri, Widen, Cecilia, Gellert, Nina, Cowie, Emma Angela, Zobalova, Renata, Dong, Lan-feng, Wang, Xiufang, Lidebjer, Caroline, Dalen, Helge, Headrick, John Patrick, Witting, Paul K.

Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2007
Author(s): Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, Stantic, Marina, Low, Pauline, Prochazka, Lubomir, Witting, Paul K., Turanek, Jaroslav, Akporiaye, Emmanuel T., Ralph, Stephen John, Neuzil, Jiri

Expression of human myoglobin in H9c2 cells enhances toxicity to added hydrogen peroxide
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2006
Author(s): Witting, Paul K., Liao, WenQiang, Harris, Matthew, Neuzil, Jiri

α-Tocopheryl succinate selectively induces apoptosis in neuroblastoma cells: Potential therapy of malignancies of the nervous system?
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2005
Author(s): Cowie, Emma Angela, Witting, Paul K., Salvatore, Brian A., Neuzil, Jiri

α-Tocopheryl succinate inhibits malignant mesothelioma by disrupting the Fibroblast Growth Factor Autocrine Loop: Mechanism and the role of oxidative stress
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2005
Author(s): Stapelberg, Michael, Gellert, Nina, Cowie, Emma Angela, Tomasetti, Marco, Witting, Paul K., Procopio, Antonio, Neuzil, Jiri

Oxidative stress in myocardial ischemia reperfusion injury: a renewed focus on a long-standing area of research.
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2005
Author(s): Neuzil, Jiri, Rayner, Benjamin S., Lowe, Harry C., Witting, Paul K.

Mitochondria play a central role in apoptosis induced by α-Tocopheryl succinate, an agent with antineoplastic activity: Comparison with receptor-mediated pro-apoptotic signaling
Publication Type: Journal Articles (Refereed Article)
Year of Publication: 2003
Author(s): Weber, Tobias, Dalen, Helge, Andera, Ladislav, Negre-Salvayre, Anne, Auge, Nathalie, Sticha, Martin, Lloret, Ana, Terman, Alexei, Witting, Paul K., Higuchi, Masahiro, Plasilova, Magdalena, Zivny, Jan, Gellert, Nina, Weber, Christian, Neuzil, Jiri