Olfactory ability in the healthy population: Reassessing presbyosmia

File Size Format
37008_1.pdf 360Kb Adobe PDF View
Title Olfactory ability in the healthy population: Reassessing presbyosmia
Author Mackay-Sim, Alan; Johnston, Amy Nicole Burne; Owen, Caroline; Burne, Thomas Henry Johnston
Journal Name Chemical Senses
Editor Dr B W Ache
Year Published 2006
Place of publication Oxford, UK
Publisher Oxford University press
Abstract Age-associated loss of olfactory function, or presbyosmia, has been described in many studies of olfactory ability. Presbyosmia has been ascribed to idiopathic causes despite recognition that many neurodegenerative diseases also induce loss of olfactory function and increase in incidence in the aged population. Often this olfactory loss is unnoticed or unreported by affected individuals. More effective olfactory function in women compared with men is another common feature of many studies of olfactory function. Here we report on normative data from an Australian population study (n = 942) that has been divided into 2 subpopulations and reassessed as (included) a population of healthy, nonmedicated, nonsmokers with no history of nasal problems (n = 485) and (excluded) a population of participants who were either medicated, smokers or had a history of nasal problems (n = 457). The "included" data set shows a strong relationship between self-reporting of olfactory sensitivity and olfactory function score. The included data set shows a small but significant decline in olfactory ability after 65 years of age and better olfactory function in females compared with males. Data from the excluded population show a marked decline in olfactory ability after 65 years of age, no difference between males and females, and a weak relationship between self-reporting of olfactory function and actual olfactory function. The power of this approach is that it provides a normative data set against which many factors such as medication schedules and pathological conditions can be compared.
Peer Reviewed Yes
Published Yes
Publisher URI http://chemse.oxfordjournals.org/
Alternative URI http://dx.doi.org/10.1093/chemse/bjl019
Copyright Statement Copyright 2006 authors.This is an open access paper. http://creativecommons.org/licenses/by/3.0/ license that permits unrestricted use, provided that the paper is properly attributed.
Volume 31
Page from 763
Page to 771
ISSN 0379-864X
Date Accessioned 2006-07-27
Language en_AU
Research Centre Centre for Health Practice Innovation; Eskitis Institute for Drug Discovery
Faculty Eskitis, Inst Cell&Molecular Therapies
Subject PRE2009-Neurobiology
URI http://hdl.handle.net/10072/13872
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

Show simple item record

Griffith University copyright notice