A Facile and Efficient Method for the Synthesis of Novel Pyridone Analogues by Aminolysis of an ester Under Solvent-Free Conditions
Author(s)
Karis, N David
Loughlin, Wendy A
Jenkins, Ian D
Year published
2007
Metadata
Show full item recordAbstract
A series of 15 pure novel N-alkylated pyridone derivatives have been synthesized in 73-96% yields on treatment of ethyl (2-pyridone)acetates with structurally diverse amines in an efficient aminolysis procedure under 'solvent-free' conditions.A series of 15 pure novel N-alkylated pyridone derivatives have been synthesized in 73-96% yields on treatment of ethyl (2-pyridone)acetates with structurally diverse amines in an efficient aminolysis procedure under 'solvent-free' conditions.
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Journal Title
Tetrahedron
Volume
63
Subject
Medicinal and biomolecular chemistry
Organic chemistry