Habbemines A and B, Pyrrolidine Alkaloids with Human δ-Opioid Receptor Binding Affinity from the Leaves of Elaeocarpus habbemensis
There are no files associated with this record.
| Title | Habbemines A and B, Pyrrolidine Alkaloids with Human δ-Opioid Receptor Binding Affinity from the Leaves of Elaeocarpus habbemensis |
|---|---|
| Author | Katavic, Peter; Venables, Debra Ann; Rali, Topul; Carroll, Anthony Richard |
| Journal Name | Journal of Natural Products |
| Editor | Douglas Kinghorn |
| Year Published | 2007 |
| Place of publication | USA |
| Publisher | American chemical Society |
| Abstract | The first phytochemical investigation of the Papua New Guinean plant Elaeocarpus habbemensis resulted in the isolation of two new pyrrolidine alkaloids, habbemine A (2) and B (3), as a 1:1 mixture of inseparable diastereomers. The structures of these compounds and their relative configurations were determined by spectroscopic means. An equimolar mixture of habbemine A and B showed human δ-opioid receptor binding affinity with an IC50 of 32.1µM. |
| Peer Reviewed | Yes |
| Published | Yes |
| Publisher URI | http://pubs.acs.org/journal/jnprdf |
| Alternative URI | http://dx.doi.org/10.1021/np060577f |
| Volume | 70 |
| Issue Number | 5 |
| Page from | 866 |
| Page to | 868 |
| ISSN | 0163-3864 |
| Date Accessioned | 2008-02-08 |
| Date Available | 2009-12-07T03:35:24Z |
| Language | en_AU |
| Research Centre | Eskitis Institute for Drug Discovery; Environmental Futures Centre |
| Faculty | Faculty of Science, Environment, Engineering and Technology |
| Subject | PRE2009-Organic Chemistry |
| URI | http://hdl.handle.net/10072/17660 |
| Publication Type | Journal Articles (Refereed Article) |
| Publication Type Code | c1 |
Please use this identifier to cite this record: http://hdl.handle.net/10072/17660
Griffith University copyright notice
Copyright in individual works within the repository belongs to their authors or publishers. You may make a print or digital copy of a work for your personal non-commercial use. All other rights are reserved, except for fair dealings or other user rights granted by the copyright laws of your country.
Footer information
Back to top