Do baseline characteristics of patients with tennis elbow influence treatment effects?

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Title Do baseline characteristics of patients with tennis elbow influence treatment effects?
Author Bisset, Leanne Margaret; Smidt, N.; Windt, D. van der; Bouter, L.; Jull, G.; Brooks, P.; Vicenzino, B.
Publication Title APA Conference Week 2007
Year Published 2007
Publisher Australian Physiotherapy Association
Abstract The aim of this study was to determine if subgroups of patients with tennis elbow respond differently to treatment. We used individual patient data (N=383) from two randomised controlled trials that investigated a wait-and-see policy, corticosteroid injections and physiotherapy. Outcome measures common and homogeneous to both trials were pain severity and global improvement. Subgroup analyses for previous history of elbow pain, baseline pain severity, duration of the current episode and employment status were performed at six and 52 weeks. Based on individual patient data from both trials, we found that corticosteroid injections were statistically and clinically superior at six weeks (p<.001), but significantly worse at 52 weeks compared to both wait and see and physiotherapy (p<.001). Subgroup effects were scarce and small. Patients with higher baseline pain showed no significant difference on pain outcomes between physiotherapy and wait-and-see at six weeks. It also appeared that non-manual workers who had an injection were the only work subgroup to demonstrate differential effects between injections and wait-and-see on global improvement at 52 weeks. The treatment outcomes were largely similar between trials and not different between most subgroups studied. In tennis elbow, it would appear that treatment outcomes are only minimally dependent on baseline patient characteristics, which supports the generalisability of individual trial results.
Peer Reviewed No
Published Yes
Conference name Australian Physiotherapy Association Conference Week
Location Cairns, Australia
Date From 2007-10-04
Date To 2007-10-08
URI http://hdl.handle.net/10072/17757
Date Accessioned 2008-03-12
Language en_AU
Research Centre Griffith Health Institute; Centre for Musculoskeletal Research
Faculty Griffith Health Faculty
Subject Rehabilitation and Therapy: Occupational and Physical
Publication Type Conference Publications (Extract Paper)
Publication Type Code e3

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