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Nanogold-pharmaceutics (i) the use of colloidal gold to treat experimentally-induced arthritis in rat models; (ii) characterization of the gold in Swarna bhasma, a microparticulate used in traditional Indian medicine

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Title Nanogold-pharmaceutics (i) the use of colloidal gold to treat experimentally-induced arthritis in rat models; (ii) characterization of the gold in Swarna bhasma, a microparticulate used in traditional Indian medicine
Author Brown, Chris; Bushell, Gillian Robin; Whitehouse, Michael; Agrawal, D S; Tupe, S G; Paknikar, K M; Tiekink, Edward R T
Journal Name Gold Bulletin
Editor Christopher W Corti
Year Published 2007
Place of publication United Kingdom
Publisher World Gold Council
Abstract Nanosized gold particles (27 +/- 3 nm) have been proven to be effective in ameliorating the symptoms of mycobacterial-, collagen- and pristane-induced arthritis in rat models. This contrasts with the drug sodium aurothiomalate that was only effective against mycobacterial-induced arthritis but not to the same extent as Au0. Gold in the traditional Indian Ayurvedic medicine, Swarna bhasma (gold ash), has been characterized as globular particles of gold with an average size of 56-57 nm.
Peer Reviewed Yes
Published Yes
Publisher URI http://www.goldbulletin.org/
Volume 40
Issue Number 3
Page from 245
Page to 250
ISSN 0017-1557
Date Accessioned 2008-02-22
Date Available 2009-12-03T06:07:35Z
Language en_AU
Research Centre Eskitis Institute for Drug Discovery; Griffith Medical Research College; Queensland Micro and Nanotechnology Centre
Faculty Griffith Health Faculty
Subject PRE2009-Medical and Health Sciences
URI http://hdl.handle.net/10072/17834
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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