Pharmacogenetics of Migraine: genetic variants and their potential role in migraine therapy

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Title Pharmacogenetics of Migraine: genetic variants and their potential role in migraine therapy
Author Fernandez, Francesca; Colson, Natalie Jane; Griffiths, Lyn
Journal Name Pharmacogenomics
Editor Laura Dormer
Year Published 2007
Place of publication London UK
Publisher Future Medicine Ltd
Abstract Migraine is a paroxysmal neurological disorder affecting up to 6% of males and 18% of females in the general population, and has been demonstrated to have a strong, but complex, genetic component. Genetic investigation of migraine provides hope that new targets for medications and individual specific therapy will be developed. The identification of polymorphisms or genetic biomarkers for disease susceptibility and treatment should aid in providing a better understanding of migraine pathology and, consequently, more appropriate and efficient treatment for migraineurs. In this review, we will discuss results investigating genetic biomarkers for migraine and their potential role in future therapy planning.
Peer Reviewed Yes
Published Yes
Publisher URI http://www.futuremedicine.com/loi/pgs
Alternative URI http://dx.doi.org/10.2217/14622416.8.6.609
Volume 8
Issue Number 6
Page from 609
Page to 622
ISSN 1462-2416
Date Accessioned 2008-01-15
Date Available 2009-01-23T05:37:49Z
Language en_AU
Research Centre Griffith Health Institute
Faculty Griffith Health Faculty
Subject PRE2009-Neurosciences
URI http://hdl.handle.net/10072/17846
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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