Biclusters visualization and detection using parallel coordinate plots
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| 49697_1.pdf | 77Kb | Adobe PDF | View |
| Title | Biclusters visualization and detection using parallel coordinate plots |
|---|---|
| Author | Cheng, K.O.; Law, N.F.; Siu, W.C.; Liew, Alan Wee-Chung |
| Publication Title | Proceedings of the International Symposium on Computational Models for Life Sciences |
| Editor | Tuan Pham & Xiaobo Zhou |
| Year Published | 2007 |
| Place of publication | USA |
| Publisher | American Institute of Physics |
| Abstract | The parallel coordinate (PC) plot is a powerful visualization tools for high-dimensional data. In this paper, we explore its usage on gene expression data analysis. We found that both the additive-related and the multiplicative-related coherent genes exhibit special patterns in the PC plots. One-dimensional clustering can then be applied to detect these patterns. Besides, a split-and-merge mechanism is employed to find the biggest coherent subsets inside the gene expression matrix. Experimental results showed that our proposed algorithm is effective in detecting various types of biclusters. In addition, the biclustering results can be visualized under a 2D setting, in which objective and subjective cluster quality evaluation can be performed. |
| Peer Reviewed | Yes |
| Published | Yes |
| Publisher URI | http://scitation.aip.org/dbt/dbt.jsp?KEY=APCPCS&Volume=952&Issue=1 |
| Alternative URI | http://dx.doi.org/10.1063/1.2816614 |
| Copyright Statement | Copyright 2007 American Institute of Physics. The attached file is reproduced here in accordance with the copyright policy of the publisher. Use hypertext link for access to the conference website. |
| ISBN | 9780735404663 |
| Conference name | International Symposium on Computational Models for Life Sciences |
| Location | Gold Coast, Australia |
| Date From | 2007-12-17 |
| Date To | 2007-12-19 |
| URI | http://hdl.handle.net/10072/18029 |
| Date Accessioned | 2008-03-06 |
| Date Available | 2009-10-16T05:19:59Z |
| Language | en_AU |
| Research Centre | Institute for Integrated and Intelligent Systems |
| Faculty | Faculty of Science, Environment, Engineering and Technology |
| Subject | PRE2009-Gene Expression; PRE2009-Pattern Recognition |
| Publication Type | Conference Publications (Full Written Paper - Refereed) |
| Publication Type Code | e1 |
Please use this identifier to cite this record: http://hdl.handle.net/10072/18029
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