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dc.contributor.authorChen, Yuru
dc.contributor.authorYu, Qiming Jimmy
dc.contributor.authorLi, Xuemei
dc.contributor.authorLuo, Yaojun
dc.contributor.authorLiu, Hui
dc.contributor.editorSteven Cramer
dc.date.accessioned2017-05-03T12:06:36Z
dc.date.available2017-05-03T12:06:36Z
dc.date.issued2007
dc.date.modified2009-08-26T07:05:06Z
dc.identifier.issn0149-6395
dc.identifier.doi10.1080/01496390701626677
dc.identifier.urihttp://hdl.handle.net/10072/18242
dc.description.abstractChlorogenic acid is a highly valuable natural polyphenol compound used in medicine and industries. Its current commercial sources are from plant extracts of Lonicera japonica Thunb and Eucommia ulmoides Oliver. These sources are limited and expensive. On the other hand, tobacco residuals contain chlorogenic acid and other natural polyphenol compounds. Large quantities of tobacco residuals are produced each year as waste materials from tobacco manufacturing, potentially providing an alternative commercial source of chlorogenic acid and other valuable compounds. In this paper, microwave and ultrasound extractions of chlorogenic acid with mixed solvent were studied. Total polyphenol concentrations in extract solutions obtained with different extraction methods were analyzed with the method of ferrous tartrate and UV-Vis spectrophotometry and compared. The extraction solutions were also characterised for polyphenol compositions with the method of HPLC. Experimental results indicated that high extract concentrations of chlorogenic acid were obtained with a mixed solvent of acetone and water (1:2 v/v). A total polyphenol concentration of up to 4.87 mg/ml and a chlorogenic acid concentration of up to 2.12 mg/ml were achieved. The application of microwave and ultrasound significantly increased the extract concentrations. The extraction time needed was also much reduced. HPLC analysis indicated that acetone water mixed solvent extraction achieved much higher relative concentrations of chlorogenic acid to other compounds in the extract solutions. These results indicted that fast and effective extraction of chlorogenic acid from tobacco residuals were achieved.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent371229 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherTaylor & Francis
dc.publisher.placeUnited States
dc.publisher.urihttp://www.tandf.co.uk/journals/titles/01496395.asp
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom3481
dc.relation.ispartofpageto3492
dc.relation.ispartofissue15
dc.relation.ispartofjournalSeparation Science and Technology
dc.relation.ispartofvolume42
dc.rights.retentionN
dc.subject.fieldofresearchAnalytical chemistry
dc.subject.fieldofresearchChemical engineering
dc.subject.fieldofresearchEnvironmental engineering
dc.subject.fieldofresearchcode3401
dc.subject.fieldofresearchcode4004
dc.subject.fieldofresearchcode4011
dc.titleExtraction and HPLC Characterization of Chlorogenic Acid from Tobacco Residues
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyright© 2007 Taylor & Francis. This is the author-manuscript version of the paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.date.issued2007
gro.hasfulltextFull Text
gro.griffith.authorYu, Jimmy J.


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