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dc.contributor.authorOey, Harald
dc.contributor.authorMaguire, David
dc.contributor.authorMcCabe, Michael
dc.date.accessioned2017-05-03T12:56:12Z
dc.date.available2017-05-03T12:56:12Z
dc.date.issued2007
dc.identifier.issn00652598
dc.identifier.doi10.1007/978-0-387-71764-7_14
dc.identifier.urihttp://hdl.handle.net/10072/19100
dc.description.abstractWith the advent of easy access to the human genome sequence, molecular biology techniques to target respirome-specific genes have begun to be exploited in the study of human disorders and in particular human cancers. In some recent publications it would appear that some investigators have inappropriately targeted pseudogenes rather than functional genes. The high transcription level and generally small size of many of the genes in the respirome make them prone to duplications in the form of processed pseudogenes within the human genome. Such genes can be challenging to analyse using standard molecular genetics approaches. In this presentation, we offer an analysis of pseudogenes that have been identified to have significant homology with some elements of the respirome. Other sequence elements such as Alu repeats, which present similar research obstacles, are also discussed.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer New York LLC
dc.publisher.placeUnited States
dc.publisher.urihttp://dx.doi.org/10.1007/978-0-387-71764-7
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom101
dc.relation.ispartofpageto107
dc.relation.ispartofjournalAdvances in Experimental Medicine and Biology
dc.relation.ispartofvolume599
dc.rights.retentionY
dc.subject.fieldofresearchMedical and Health Sciences
dc.subject.fieldofresearchcode11
dc.titlePseudogenes and the Electron Transport Chain
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2015-02-02T04:16:52Z
gro.hasfulltextNo Full Text
gro.griffith.authorMaguire, David J.
gro.griffith.authorMcCabe, Michael
gro.griffith.authorOey, Harald M.


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