Avian influenza virus, a very sticky situation

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Title Avian influenza virus, a very sticky situation
Author von Itzstein, Mark
Journal Name Current Opinion in Chemical Biology
Year Published 2008
Place of publication United Kingdom
Publisher Elsevier Ltd
Abstract The appearance of the highly pathogenic avian influenza virus H5N1 highlighted the potential impact of influenza virus on humanity. The emergence of this high profile virus stimulated much research towards a better understanding of the key determinants for successful human-to-human transmission and as such has provided new directions for therapeutic intervention strategies. For example, a phylogenetic-based grouping of influenza virus sialidases into either Group 1 or 2 has been proposed. This has provided new opportunity for the development of Group 1-specific anti-influenza drugs. Furthermore, a number of next generation sialidase inhibitors as anti-influenza drugs have also been developed.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.1016/j.cbpa.2008.01.036
Volume 12
Page from 102
Page to 108
ISSN 1367-5931
Date Accessioned 2008-07-07
Language en_AU
Research Centre Institute for Glycomics
Faculty Faculty of Science, Environment, Engineering and Technology
Subject PRE2009-Organic Chemical Synthesis
URI http://hdl.handle.net/10072/20256
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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