Total synthesis of altohyrtin A (spongistatin 1): an alternative synthesis of the CD-spiroacetal subunit.
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| Title | Total synthesis of altohyrtin A (spongistatin 1): an alternative synthesis of the CD-spiroacetal subunit. |
|---|---|
| Author | Paterson, Ian; Coster, Mark J. |
| Journal Name | Tetrahedron Letters |
| Year Published | 2002 |
| Place of publication | Oxford, UK |
| Publisher | Elsevier Ltd |
| Abstract | The CD-spiroacetal contg. C16-C28 subunit I, as used in the total synthesis of the potent cytotoxic macrolide altohyrtin A (spongistatin 1), was prepd. by an alternative route using substrate-based stereocontrol in the two aldol bond constructions generating the acyclic precursor II. |
| Peer Reviewed | Yes |
| Published | Yes |
| Publisher URI | http://www.sciencedirect.com/science/journal/00404039 |
| Alternative URI | http://dx.doi.org/10.1016/S0040-4039(02)00527-0 |
| Volume | 43 |
| Page from | 3285 |
| Page to | 3289 |
| ISSN | 0040-4039 |
| Date Accessioned | 2007-06-08 |
| Date Available | 2009-04-20T04:47:01Z |
| Language | en_AU |
| Research Centre | Eskitis Institute for Drug Discovery |
| Faculty | Eskitis, Inst Cell&Molecular Therapies |
| Subject | PRE2009-Organic Chemical Synthesis |
| URI | http://hdl.handle.net/10072/22614 |
| Publication Type | Journal Articles (Refereed Article) |
| Publication Type Code | c1x |
Please use this identifier to cite this record: http://hdl.handle.net/10072/22614
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