Dose thresholds and effect mechanisms for pain management with LASER phototherapy

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Title Dose thresholds and effect mechanisms for pain management with LASER phototherapy
Author Laakso, Liisa
Publication Title Proceedings of the International Conference of the World Association of Laser Therapy
Editor Heidi Abrahamse
Year Published 2008
Place of publication Italy
Publisher Medimond
Abstract Arguably, the two most important aspects regarding laser phototherapy for pain management are those of effect mechanism (to determine the most appropriate application) and of dosing parameters. Herein is summarised the outcomes of more than 15 years of the author's research to date, to clarify some of these factors. Initial investigations demonstrated that the central descending inhibitory (endogenous opioid) system was involved in the effect mechanism of phototherapy and that doses below 5J/cm2 in the wavelengths tested, had the best effects in a chronic pain clinical model. Subsequent research using a non-invasive clinical model in lateral epicondylalgia has established that the descending inhibitory system is not the sole likely origin of the treatment response; or, if it is, it plays this role selectively for only some combinations of wavelength, dose and power output. Repeated low doses of laser (at some wavelengths) are sufficient to stimulate physiological responses and reduce pain in subjects with lateral epicondylalgia. It is clear further information is required for dosing and dose threshold factors of laser phototherapy for clinical pain management.
Peer Reviewed Yes
Published Yes
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Copyright Statement Copyright 2008 MEDIMOND. The attached file is posted here in accordance with the copyright policy of the publisher, for your personal use only. No further distribution permitted For information about this conference please refer to the publisher's website.
ISBN 978-88-7587-471-1
Conference name WALT South Africa 2008
Location Sun City (South Africa)
Date From 2008-10-19
Date To 2008-10-22
Date Accessioned 2009-01-16
Language en_AU
Research Centre Menzies Health Institute Qld; Centre for Musculoskeletal Research
Faculty Griffith Health Faculty
Subject Complementary and Alternative Medicine
Publication Type Conference Publications (Full Written Paper - Refereed)
Publication Type Code e1

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