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dc.contributor.authorGan, Xiangchao
dc.contributor.authorLiew, Alan Wee-Chung
dc.contributor.authorYan, Hong
dc.contributor.editorTang, YY
dc.contributor.editorWang, SP
dc.contributor.editorLorette, G
dc.contributor.editorYeung, DS
dc.contributor.editorYan, H
dc.date.accessioned2017-05-03T15:20:33Z
dc.date.available2017-05-03T15:20:33Z
dc.date.issued2006
dc.date.modified2010-10-27T08:28:58Z
dc.identifier.isbn9780769525211
dc.identifier.issn1051-4651
dc.identifier.doi10.1109/ICPR.2006.433
dc.identifier.urihttp://hdl.handle.net/10072/24405
dc.description.abstractIn microarray experiments, gene expression profiles are often affected by biological properties, such as synchronization loss, and show some non-stationarity. Worse still, the microarray data usually suffers from missing values. The conventional spectrum-based methods, when used to identify a subset of genes that are periodically expressed, are degraded by these factors. In this paper, we use the Wigner-Ville distribution analysis and L-curve method for detection of periodically expressed genes. We provide a graphical exploratory device for assessment of the presence of periodically expressed genes. Then, we identify the subset of genes actually involved in the cell cycle using the L-curve method. The experiments on several widely used datasets show that our algorithm can effectively reduce the effect of non-stationarity and missing values problems.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent151865 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherIEEE Computer Society
dc.publisher.placeUSA
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofconferencename18th International Conference on Pattern Recognition (ICPR 2006)
dc.relation.ispartofconferencetitle18TH INTERNATIONAL CONFERENCE ON PATTERN RECOGNITION, VOL 2, PROCEEDINGS
dc.relation.ispartofdatefrom2006-08-20
dc.relation.ispartofdateto2006-08-24
dc.relation.ispartoflocationHong Kong, PEOPLES R CHINA
dc.relation.ispartofpagefrom654
dc.relation.ispartofpageto+
dc.relation.ispartofvolume2
dc.rights.retentionY
dc.subject.fieldofresearchcode270201
dc.subject.fieldofresearchcode280204
dc.titleDetecting Periodically Expressed Genes based on Time-frequency Analysis and L-curve Method
dc.typeConference output
dc.type.descriptionE1 - Conferences
dc.type.codeE - Conference Publications
gro.rights.copyright© 2006 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
gro.date.issued2006
gro.hasfulltextFull Text
gro.griffith.authorLiew, Alan Wee-Chung


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