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dc.contributor.authorKoroloff, N
dc.contributor.authorBoots, R
dc.contributor.authorLipman, J
dc.contributor.authorThomas, P
dc.contributor.authorRickard, C
dc.contributor.authorCoyer, F
dc.date.accessioned2017-05-03T15:24:55Z
dc.date.available2017-05-03T15:24:55Z
dc.date.issued2004
dc.date.modified2009-11-24T05:21:31Z
dc.identifier.issn0342-4642
dc.identifier.doi10.1007/s00134-004-2203-y
dc.identifier.urihttp://hdl.handle.net/10072/26821
dc.description.abstractObjective To compare the efficacy of two forms of eye care (hypromellose and Lacri-Lube combination vs polyethylene/Cling wrap covers) for intensive care patients. Design Randomised-controlled trial. Setting University affiliated, tertiary referral hospital. Patients and participants One hundred ten patients with a reduced or absent blink reflex were followed through until they regained consciousness, were discharged from the facility during study enrolment, died or developed a positive corneal ulcer or eye infection. Interventions All patients received standard eye cleansing every 2 h. In addition to this, group one (n=60) received a treatment combining hypromellose drops and Lacri-Lube (HL) to each eye every 2 h. Group two (n=50) had polyethylene covers only placed over the eye to create a moisture chamber. Measurements and results Corneal ulceration was determined using corneal fluorescein stains and mobile slit lamp evaluation, performed daily. No patients had corneal ulceration in the polyethylene cover group, but 4 patients had corneal ulceration in the HL group. Conclusions Polyethylene covers are as effective as HL in reducing the incidence of corneal damage in intensive care patients.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer
dc.publisher.placeGermany
dc.relation.ispartofpagefrom1122
dc.relation.ispartofpageto1126
dc.relation.ispartofissue6
dc.relation.ispartofjournalIntensive Care Medicine
dc.relation.ispartofvolume30
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3202
dc.titleA randomised controlled study of the efficacy of hypromellose and Lacri-Lube combination versus polyethylene/Cling wrap to prevent corneal epithelial breakdown in the semiconscious intensive care patient
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2004
gro.hasfulltextNo Full Text
gro.griffith.authorRickard, Claire


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