Facile synthesis of core intermediates toward sialyl nucleoside mimetics

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Title Facile synthesis of core intermediates toward sialyl nucleoside mimetics
Author Kwon, Hyeok Beom; von Itzstein, Mark; Jung, Kang-Yeoun
Journal Name Tetrahedron Letters
Year Published 2009
Place of publication UK
Publisher Elsevier Ltd
Abstract 6-Deoxyphosphonated intermediates, 8 and 12, were efficiently synthesized from D-fructose and sucrose, respectively. These novel intermediates will be useful to synthesize various D-tagato- and fructofuranoside derivatives as inhibitors of sialyl transferase or sialidase.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.1016/j.tetlet.2009.03.050
Volume 50
Issue Number 21
Page from 2543
Page to 2544
ISSN 0040-4039
Date Accessioned 2010-02-18
Language en_AU
Research Centre Institute for Glycomics
Faculty Faculty of Science, Environment, Engineering and Technology
Subject Biologically Active Molecules
URI http://hdl.handle.net/10072/30541
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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