Serum uric acid, hyperuricemia and body mass index in children and adolescents with intellectual disabilities

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Title Serum uric acid, hyperuricemia and body mass index in children and adolescents with intellectual disabilities
Author Lin, Jin-Ding; Lin, Pei-Ying; Lin, Lan-Ping; Hsu, Shang-Wei; Yen, Chia-Feng; Fang, Wen-Hui; Wu, Sheng-Ru; Chien, Wu-Chien; Loh, Ching-Hui; Chu, Cordia Ming-Yeuk
Journal Name Research in Developmental Disabilities
Year Published 2009
Place of publication United Kingdom
Publisher Elsevier
Abstract The aims of the preset study were to describe the profile of serum uric acid, the prevalence of hyperuricemia and its risk factors among children and adolescents with intellectual disabilities. We conducted a cross-sectional study of 941 children and adolescents with intellectual disabilities (aged 4–18 years) who participated in annual health examinations in three special schools in Taiwan. This study indicated 30.6% boys and 17.9% girls with intellectual disabilities were with hyperuricemia in Taiwan. The factors of gender, age and BMI were variables that can significantly predict the hyperuricemia occurrence in this vulnerable population. Those children and adolescents with intellectual disabilities were boys (OR = 2.93, 95% CI = 2.02–4.26) and older age (OR = 6.49, 95% CI = 2.19–19.21) were more likely to be hyperuricemia. With regard to BMI to hyperuricemia occurrence, those children and adolescents with intellectual disabilities were overweight (OR = 1.16–3.21, 95% CI = 1.16–3.21) and being obese (OR = 4.95–11.58, 95% CI = 4.95– 11.58) was more likely to have a hyperuricemia than the normal weight group. This study provides the general profile of serum uric acid, hyperuricemia and its risk factors of children and adolescents with intellectual disabilities. Medical professionals should be highly alert to the possible consequences of hyperuricemia and provide useful information about the clinical manifestation of this condition for caregivers of children and adolescents with intellectual disabilities.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.1016/j.ridd.2009.07.008
Volume 30
Issue Number 6
Page from 1481
Page to 1489
ISSN 0891-4222
Date Accessioned 2009-09-23
Language en_AU
Research Centre Griffith Asia Institute
Faculty Faculty of Science, Environment, Engineering and Technology
Subject PRE2009-Care for Disabled; PRE2009-Epidemiology
URI http://hdl.handle.net/10072/30668
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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