Bone quality in vertebral fracture: Microdamage, mineralisation and microarchitecture of the cortical shell in lumbar vertebrae
Author(s)
Forwood, MR
Roux, JP
Arlot, ME
Burt-Pitchat, B
Follet, H
Bala, Y
Delmas, PD
Griffith University Author(s)
Year published
2009
Metadata
Show full item recordAbstract
Resistance to vertebral fracture is provided by a bone structure that integrates the cortical shell, or cortex, with trabecular bone. The cortical shell of vertebral bodies demonstrates a contribution to load sharing that is disproportionate to its relative bone volume fraction, but there is a paucity of data on the bone quality of the cortex relative to the adjacent trabeculae. The aim of this project was to quantify the microdamage burden, mineralisation and microarchitecture of the cortical shell of the human L2 vertebra.Resistance to vertebral fracture is provided by a bone structure that integrates the cortical shell, or cortex, with trabecular bone. The cortical shell of vertebral bodies demonstrates a contribution to load sharing that is disproportionate to its relative bone volume fraction, but there is a paucity of data on the bone quality of the cortex relative to the adjacent trabeculae. The aim of this project was to quantify the microdamage burden, mineralisation and microarchitecture of the cortical shell of the human L2 vertebra.
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Conference Title
BONE
Volume
44
Subject
Biological sciences
Engineering
Biomedical and clinical sciences
Endocrinology
Orthopaedics