Synthesis of N-Propargyl Iminosugar Scaffolds for Compound Library Generation using Click Chemistry
There are no files associated with this record.
| Title | Synthesis of N-Propargyl Iminosugar Scaffolds for Compound Library Generation using Click Chemistry |
|---|---|
| Author | Wilkinson, Brendan Luke; Bornaghi, Laurent; Lopez, Marie; Healy, Peter Conrad; Poulsen, Sally-Ann; Houston, Todd Ashley |
| Journal Name | Australian Journal of Chemistry |
| Year Published | 2010 |
| Place of publication | Australia |
| Publisher | CSIRO Publishing |
| Abstract | We have developed an efficient synthesis of N-propargyl iminosugars for use in diversity-oriented library development. Through a common, crystalline intermediate both piperidine and azepane scaffolds can be prepared with an alkyne functional group, allowing for further elaboration through reaction with azides. |
| Peer Reviewed | Yes |
| Published | Yes |
| Alternative URI | http://dx.doi.org/10.1071/CH09426 |
| Volume | 63 |
| Issue Number | 5 |
| Page from | 821 |
| Page to | 829 |
| ISSN | 0004-9425 |
| Date Accessioned | 2010-06-10 |
| Date Available | 2010-09-01T08:07:38Z |
| Language | en_AU |
| Research Centre | Queensland Micro and Nanotechnology Centre; Eskitis Institute for Drug Discovery; Institute for Glycomics |
| Faculty | Faculty of Science, Environment, Engineering and Technology |
| Subject | Biologically Active Molecules |
| URI | http://hdl.handle.net/10072/32201 |
| Publication Type | Journal Articles (Refereed Article) |
| Publication Type Code | c1 |
Please use this identifier to cite this record: http://hdl.handle.net/10072/32201
Griffith University copyright notice
Copyright in individual works within the repository belongs to their authors or publishers. You may make a print or digital copy of a work for your personal non-commercial use. All other rights are reserved, except for fair dealings or other user rights granted by the copyright laws of your country.
Footer information
Back to top