2-Propynyl 2-hydroxybenzoate

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Title 2-Propynyl 2-hydroxybenzoate
Author Levonis, Stephan; Kiefel, Milton; Houston, Todd Ashley; Healy, Peter Conrad
Journal Name Acta crystallographica. Section E, Structure reports online
Year Published 2010
Place of publication United States,
Publisher Wiley-Blackwell Publishing, Inc
Abstract The title compound, C10H8O3, has been synthesized as part of our investigations into the generation of new antibacterial agents and serves as a building block for the synthesis of compound libraries. The compound crystallizes with two independent molecules in the asymmetric unit. The transoid propynyl ester groups are coplanar with the 2-hydroxybenzoate group with maximum deviations of -0.3507 (3) and 0.1591 (3) Å for the terminal carbons, with intramolecular O-HO hydrogen bonding providing rigidity to the structure and ensuring that the reactivity of the alkyne is not compromised by steric factors. The propynyl group forms intermolecular C-HO interactions with the phenolic O atom. Supramolecular chains along the b axis are found for both molecules with links by weak O-HO intermolecular interactions in the first independent molecule and C-HO interactions in the second.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.1107/S160053680905421X
Copyright Statement Copyright remains with the authors 2010. For information about this journal please refer to the journal's website. All articles published in Acta Crystallographica Section E are open access and distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. See http://creativecommons.org/licenses/by/2.0/uk/legalcode
Volume 66
Page from o226
Page to o227
ISSN 1600-5368
Date Accessioned 2010-05-10
Language en_AU
Research Centre Institute for Glycomics
Faculty Faculty of Science, Environment, Engineering and Technology
Subject Structural Chemistry and Spectroscopy
URI http://hdl.handle.net/10072/32416
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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