Prospective memory deficits in patients with bipolar disorder: A preliminary study

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Title Prospective memory deficits in patients with bipolar disorder: A preliminary study
Author Lee, Edwin; Xiang, Yu-Tao; Man, David; Au, Raymond W. C.; Shum, David; Tang, Wai-Kwong; Chiu, Helen F. K.; Wong, Pinki; Ungvari, Gabor S.
Journal Name Archives of Clinical Neuropsychology
Year Published 2010
Place of publication United Kingdom
Publisher Oxford University Press
Abstract Prospective memory (PM) is the ability to remember to do something in the future without explicit prompts. To date, little has been known about PM deficits in bipolar disorder (BD). This study examined the nature and correlates of PM in patients with BD. Forty clinically stable BD patients and 40 matched healthy controls formed the study sample. Socio-demographic characteristics, PM, psychosocial functioning, retrospective memory (RM), and IQ were measured in all participants, whereas clinical condition was measured in patients with standardized assessment instruments. Patients performed significantly more poorly on the time-based PM task than controls (10.6+5.0 vs. 14.6+3.0, p , .001). In correlation analyses, older age, lower education, more severe depressive and manic symptoms, poor psychosocial functioning, poor RM, and lower scores in IQ were significantly associated with poor performance in the time-based PM task, whereas poor RM and lower scores in IQ associated with poorer performance in the event-based PM task in patients. In multivariate analyses, severity of depression and older age significantly contributed to poor performance in the time-based PM task, whereas poor RM contributed to poor performance in the event-based PM task in patients. The time-based PM is impaired in BD patients. Depressive symptoms, age, and RM were determinants of certain aspects of impaired PM performance in BD patients.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.1093/arclin/acq061
Volume 25
Issue Number 7
Page from 640
Page to 647
ISSN 0887-6177
Date Accessioned 2010-11-13
Language en_AU
Research Centre Behavioural Basis of Health; Griffith Health Institute
Faculty Griffith Health Faculty
Subject Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
URI http://hdl.handle.net/10072/35306
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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