Genetics of Menstrual Migraine: The Molecular Evidence

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Title Genetics of Menstrual Migraine: The Molecular Evidence
Author Colson, Natalie Jane; Fernandez, Francesca; Griffiths, Lyn
Journal Name Current Pain and Headache Reports
Year Published 2010
Place of publication United States
Publisher Springer
Abstract Migraine is considered to be a multifactorial disorder in which genetic, environmental, and, in the case of menstrual and menstrually related migraine, hormonal events influence the phenotype. Certainly, the role of female sex hormones in migraine has been well established, yet the mechanism behind this well-known relationship remains unclear. This review focuses on the potential role of hormonally related genes in migraine, summarizes results of candidate gene studies to date, and discusses challenges and issues involved in interpreting hormone-related gene results. In light of the molecular evidence presented, we discuss future approaches for analysis with the view to elucidate the complex genetic architecture that underlies the disorder.
Peer Reviewed Yes
Published Yes
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Copyright Statement Copyright 2010 Current Medicine Group LLC. Published by Springer. This is an electronic version of an article published in Current Pain and Headache Reports, Volume 14, Number 5, 389-395. Current Pain and Headache Reports is available online at: with the open URL of your article.
Volume 14
Issue Number 5
Page from 389
Page to 395
ISSN 1531-3433
Date Accessioned 2010-12-06
Language en_AU
Research Centre Menzies Health Institute Qld
Faculty Griffith Health Faculty
Subject Medical and Health Sciences
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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