Caelestines A-D, brominated quinolinecarboxylic acids from the Australian ascidian aplidium caelestis
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| Title | Caelestines A-D, brominated quinolinecarboxylic acids from the Australian ascidian aplidium caelestis |
|---|---|
| Author | Yin, Sheng; Boyle, Glen M.; Carroll, Anthony Richard; Kotiw, Michael; Dearnaley, John; Quinn, Ronald J.; Davis, Rohan Andrew |
| Journal Name | Journal of Natural Products |
| Year Published | 2010 |
| Place of publication | United States |
| Publisher | American Chemical Society |
| Abstract | Four new brominated natural products, caelestines A-D (1-4), have been isolated from the Australian ascidian Aplidium caelestis. The structures of 1-4 were determined by analysis of their NMR and MS data. This is the first report of brominated quinolinecarboxylic acids from nature. Compound 1 has been previously synthesized but not spectroscopically characterized. Compounds 1-4 were tested against three mammalian cell lines (MCF-7, NFF, and MM96L) and a panel of microbial strains and showed only minor cytotoxicity. |
| Peer Reviewed | Yes |
| Published | Yes |
| Alternative URI | http://dx.doi.org/10.1021/np100329w |
| Copyright Statement | Self-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the authors for more information. |
| Volume | 73 |
| Issue Number | 9 |
| Page from | 1586 |
| Page to | 1589 |
| ISSN | 0163-3864 |
| Date Accessioned | 2010-10-27 |
| Date Available | 2011-04-11T06:48:21Z |
| Language | en_AU |
| Research Centre | Environmental Futures Centre; Eskitis Institute for Drug Discovery |
| Faculty | Faculty of Science, Environment, Engineering and Technology |
| Subject | Natural Products Chemistry |
| URI | http://hdl.handle.net/10072/36773 |
| Publication Type | Journal Articles (Refereed Article) |
| Publication Type Code | c1 |
Please use this identifier to cite this record: http://hdl.handle.net/10072/36773
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