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dc.contributor.authorBisht, Kavita
dc.contributor.authorWagner, Karl-Heinz
dc.contributor.authorBulmer, Andrew C
dc.date.accessioned2017-05-03T12:40:41Z
dc.date.available2017-05-03T12:40:41Z
dc.date.issued2010
dc.date.modified2011-07-06T10:05:48Z
dc.identifier.issn0300-483X
dc.identifier.doi10.1016/j.tox.2009.11.008
dc.identifier.urihttp://hdl.handle.net/10072/36884
dc.description.abstractNumerous dietary compounds, ubiquitous in fruits, vegetables and spices have been isolated and evaluated during recent years for their therapeutic potential. These compounds include flavonoid and non-flavonoid polyphenols, which describe beneficial effects against a variety of ailments. The notion that these plant products have health promoting effects emerged because their intake was related to a reduced incidence of cancer, cardiovascular, neurological, respiratory, and age-related diseases. Exposure of the body to a stressful environment challenges cell survival and increases the risk of chronic disease developing. The polyphenols afford protection against various stress-induced toxicities through modulating intercellular cascades which inhibit inflammatory molecule synthesis, the formation of free radicals, nuclear damage and induce antioxidant enzyme expression. These responses have the potential to increase life expectancy. The present review article focuses on curcumin, resveratrol, and flavonoids and seeks to summarize their anti-inflammatory, cytoprotective and DNA-protective properties.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent318243 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeIreland
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom88
dc.relation.ispartofpageto100
dc.relation.ispartofissue1
dc.relation.ispartofjournalToxicology
dc.relation.ispartofvolume278
dc.rights.retentionY
dc.subject.fieldofresearchPharmacology and pharmaceutical sciences
dc.subject.fieldofresearchPharmacology and pharmaceutical sciences not elsewhere classified
dc.subject.fieldofresearchcode3214
dc.subject.fieldofresearchcode321499
dc.titleCurcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyright© 2010 Elsevier Ireland Ltd. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.date.issued2010
gro.hasfulltextFull Text
gro.griffith.authorBulmer, Andrew C.


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