What have we learnt from mouse models for the study of malaria?

There are no files associated with this record.

Title What have we learnt from mouse models for the study of malaria?
Author Wykes, Michelle N.; Good, Michael Francis
Journal Name European Journal of Immunology
Year Published 2009
Place of publication Germany
Publisher Wiley - V C H Verlag GmbH & Co. KGaA
Abstract Malaria is a serious cause of morbidity and mortality and yet a vaccine is not available. Studies have used animal models to understand the pathogenesis of disease and a large amount of data on parasite biology, immune regulation and disease processes have been gained from these studies. Moreover, these models have been used for pre-clinical testing of various drugs and vaccines. Here, we discuss the features of various mouse models used to study the immunobiology of malaria and test pre-clinical vaccines and conclude that animal models have a role in the study of malaria but the experimental conditions used for testing must reflect the environment of infected individuals.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.1002/eji.200939552
Volume 39
Issue Number 8
Page from 2004
Page to 2007
ISSN 0014-2980
Date Accessioned 2011-03-31
Date Available 2011-05-31T06:24:24Z
Language en_AU
Research Centre Institute for Glycomics
Faculty Faculty of Science, Environment, Engineering and Technology
Subject Infectious Diseases
URI http://hdl.handle.net/10072/38919
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1x

Show simple item record

Griffith University copyright notice