What really happens to dendritic cells during malaria?
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| Title | What really happens to dendritic cells during malaria? |
|---|---|
| Author | Wykes, Michelle N.; Good, Michael Francis |
| Journal Name | Nature Reviews Microbiology |
| Year Published | 2008 |
| Place of publication | United Kingdom |
| Publisher | Nature Publishing Group |
| Abstract | As dendritic cells (DCs) initiate all adaptive and some innate immune responses, it is not surprising that DC function during malaria is the subject of intensive investigations. However, the results of these investigations have so far been controversial. Here, we discuss various aspects of these studies, including the influence of the species and strain of Plasmodium on DC function, the effects of Plasmodium infection on the activation of CD8+ T cells by DCs, the effects of haemozoin and the effects of Plasmodium infections on DC Toll-like-receptor signalling. |
| Peer Reviewed | Yes |
| Published | Yes |
| Alternative URI | http://dx.doi.org/10.1038/nrmicro1988 |
| Volume | 6 |
| Issue Number | 11 |
| Page from | 864 |
| Page to | 870 |
| ISSN | 1740-1526 |
| Date Accessioned | 2011-07-13 |
| Date Available | 2011-08-12T06:20:47Z |
| Language | en_AU |
| Research Centre | Institute for Glycomics |
| Faculty | Faculty of Science, Environment, Engineering and Technology |
| Subject | Microbiology |
| URI | http://hdl.handle.net/10072/39939 |
| Publication Type | Journal Articles (Refereed Article) |
| Publication Type Code | c1x |
Please use this identifier to cite this record: http://hdl.handle.net/10072/39939
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