An approach towards the synthesis of sialyl nucleoside mimetics

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Title An approach towards the synthesis of sialyl nucleoside mimetics
Author Grice, Darren; Whelan, Catherine Ann; Tredwell, Greg; von Itzstein, Mark
Journal Name Tetrahedron: Asymmetry
Editor S.G. Davies, T. Hayashi
Year Published 2005
Place of publication United Kingdom
Publisher Elsevier
Abstract An approach towards the synthesis of novel sialyl nucleoside mimetics based on d-fructose is described. The synthesis of these mimetics is achieved in good overall yield in seven steps. The key synthetic step is the coupling reaction of pyrimidine bases (uracil, 5-fluorouracil and cytosine) to the C-1 position of the modified d-tagatofructofuranoside
Peer Reviewed Yes
Published Yes
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Copyright Statement Copyright 2005 Elsevier : Reproduced in accordance with the copyright policy of the publisher : This journal is available online - use hypertext links.
Volume 16
Edition 2005
Page from 1425
Page to 1434
ISSN 0957-4166
Date Accessioned 2006-03-03
Language en_AU
Research Centre Institute for Glycomics
Faculty Institute for Glycomics
Subject PRE2009-Biological and Medical Chemistry; PRE2009-Organic Chemical Synthesis
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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