dc.contributor.author | Scott, SA | |
dc.contributor.author | Holloway, G | |
dc.contributor.author | Coulson, BS | |
dc.contributor.author | Szyczew, AJ | |
dc.contributor.author | Kiefel, MJ | |
dc.contributor.author | von Itzstein, M | |
dc.contributor.author | Blanchard, H | |
dc.date.accessioned | 2018-01-23T01:00:20Z | |
dc.date.available | 2018-01-23T01:00:20Z | |
dc.date.issued | 2005 | |
dc.identifier.issn | 1744-3091 | |
dc.identifier.doi | 10.1107/S1744309105013849 | |
dc.identifier.uri | http://hdl.handle.net/10072/4187 | |
dc.description.abstract | Rotavirus recognition and attachment to host cells involves interaction with the spike protein VP4 that projects outwards from the surface of the virus particle. An integral component of these spikes is the VP8* domain, which is implicated in the direct recognition and binding of sialic acid-containing cell-surface carbohydrates and facilitates subsequent invasion by the virus. The expression, purification, crystallization and preliminary X-ray diffraction analysis of VP8* from porcine CRW-8 rotavirus is reported. Diffraction data have been collected to 2.3 Šresolution, enabling the determination of the VP8* structure by molecular replacement. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Blackwell Publishing | |
dc.publisher.place | Oxford, England | |
dc.relation.ispartofstudentpublication | Y | |
dc.relation.ispartofpagefrom | 617 | |
dc.relation.ispartofpageto | 620 | |
dc.relation.ispartofissue | 6 | |
dc.relation.ispartofjournal | Acta Crystallographica Section F: Structural Biology and Crystallization Communications | |
dc.relation.ispartofvolume | F61 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Chemical sciences | |
dc.subject.fieldofresearch | Biological sciences | |
dc.subject.fieldofresearchcode | 34 | |
dc.subject.fieldofresearchcode | 31 | |
dc.title | Crystallisation and preliminary X-ray diffraction analysis of the sialic acid-binding domain (VP8*) of porcine rotavirus strain CRW-8 | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Office of the Snr Dep Vice Chancellor, Institute for Glycomics | |
gro.date.issued | 2015-01-30T00:42:29Z | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | von Itzstein, Mark | |
gro.griffith.author | Kiefel, Milton | |