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dc.contributor.authorScott, SA
dc.contributor.authorHolloway, G
dc.contributor.authorCoulson, BS
dc.contributor.authorSzyczew, AJ
dc.contributor.authorKiefel, MJ
dc.contributor.authorvon Itzstein, M
dc.contributor.authorBlanchard, H
dc.date.accessioned2018-01-23T01:00:20Z
dc.date.available2018-01-23T01:00:20Z
dc.date.issued2005
dc.identifier.issn1744-3091
dc.identifier.doi10.1107/S1744309105013849
dc.identifier.urihttp://hdl.handle.net/10072/4187
dc.description.abstractRotavirus recognition and attachment to host cells involves interaction with the spike protein VP4 that projects outwards from the surface of the virus particle. An integral component of these spikes is the VP8* domain, which is implicated in the direct recognition and binding of sialic acid-containing cell-surface carbohydrates and facilitates subsequent invasion by the virus. The expression, purification, crystallization and preliminary X-ray diffraction analysis of VP8* from porcine CRW-8 rotavirus is reported. Diffraction data have been collected to 2.3 Šresolution, enabling the determination of the VP8* structure by molecular replacement.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBlackwell Publishing
dc.publisher.placeOxford, England
dc.relation.ispartofstudentpublicationY
dc.relation.ispartofpagefrom617
dc.relation.ispartofpageto620
dc.relation.ispartofissue6
dc.relation.ispartofjournalActa Crystallographica Section F: Structural Biology and Crystallization Communications
dc.relation.ispartofvolumeF61
dc.rights.retentionY
dc.subject.fieldofresearchChemical sciences
dc.subject.fieldofresearchBiological sciences
dc.subject.fieldofresearchcode34
dc.subject.fieldofresearchcode31
dc.titleCrystallisation and preliminary X-ray diffraction analysis of the sialic acid-binding domain (VP8*) of porcine rotavirus strain CRW-8
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyOffice of the Snr Dep Vice Chancellor, Institute for Glycomics
gro.date.issued2015-01-30T00:42:29Z
gro.hasfulltextNo Full Text
gro.griffith.authorvon Itzstein, Mark
gro.griffith.authorKiefel, Milton


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