Health risk characterisation for environmental pollutants with a new concept of overall risk probability

There are no files associated with this record.

Title Health risk characterisation for environmental pollutants with a new concept of overall risk probability
Author Cao, Qiming; Yu, Jimmy; Connell, Des
Journal Name Journal of Hazardous Materials
Year Published 2011
Place of publication Netherlands
Publisher Elsevier
Abstract In health risk assessment, risk is commonly characterised by calculating a simple hazard quotient (HQ), which cannot reflect the actual distribution of exposure and health effect values. This study aimed to develop a new risk characterisation method, the overall risk probability (ORP) method based on probabilistic techniques. Exposure exceedence values were calculated to obtain an exposure exceedence curve (EEC). The area under the EEC was calculated as the ORP value to represent the risk. This method was demonstrated by a case study for two steroidal EDCs, 17β-estradiol (E2) and 17α-ethinylestradiol (EE2) for fish in surface water. It was found that the risk probability of fish exposed to E2 (ORP, 8.1%) and EE2 (ORP, 27%) were both above the reference value of 2.5%, which was consistent with the results of HQ method. Assuming independent action of individual EDCs, a combined risk probability of 33% was obtained for the mixture effects of E2 and EE2. Our results implicated that the adverse health effects imposed by E2 and EE2 were significant for fish in surface water worldwide.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.1016/j.jhazmat.2011.01.054
Volume 187
Issue Number 1-3
Page from 480
Page to 487
ISSN 0304-3894
Date Accessioned 2011-06-21
Date Available 2012-02-10T01:05:35Z
Language en_US
Research Centre Atmospheric Environment Research Centre
Faculty Faculty of Science, Environment, Engineering and Technology
Subject Environmental Technologies
URI http://hdl.handle.net/10072/42261
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

Brief Record

Griffith University copyright notice