An efficient approach to 2,5-anhydro-glucitol-based 1'-homo-N-nucleoside mimetics

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Title An efficient approach to 2,5-anhydro-glucitol-based 1'-homo-N-nucleoside mimetics
Author Bhatt, Beenu; Thomson, Robin Joy; von Itzstein, Mark
Journal Name Tetrahedron Letters
Year Published 2011
Place of publication United States
Publisher Elsevier
Abstract This Letter describes an efficient synthesis of a range of 10-homo-N-nucleoside mimetics with a series of 4-substituted 1,2,3-triazoles replacing the natural nucleobase. The synthesis of 6-O-monosulfated 10- homo-N-nucleoside mimetic derivatives is also discussed.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.1016/j.tetlet.2011.03.090
Volume 52
Issue Number 21
Page from 2741
Page to 2743
ISSN 0040-4039
Date Accessioned 2011-12-20; 2012-02-14T05:37:06Z
Date Available 2012-02-14T05:37:06Z
Research Centre Institute for Glycomics
Faculty Faculty of Science, Environment, Engineering and Technology
Subject Organic Chemical Synthesis
URI http://hdl.handle.net/10072/42611
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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