Global Oral Health Inequalities in Incidence and Outcomes for Oral Cancer Causes and Solutions

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Title Global Oral Health Inequalities in Incidence and Outcomes for Oral Cancer Causes and Solutions
Author Johnson, Newell Walter; Warnakulasuriya, S.; Gupta, P.C.; Dimba, E.; Chindia, M.; Otoh, E.C.; Sankaranarayanan, R.; Califano, J.; Kowalski, L.
Journal Name Advances in Dental Research
Year Published 2011
Place of publication United States
Publisher International and American Associations for Dental Research
Abstract The mouth and oropharynx are among the ten most common sites affected by cancer worldwide, but global incidence varies widely. Five-year survival rates exceed 50% in only the best treatment centers. Causes are predominantly lifestyle-related: Tobacco, areca nut, alcohol, poor diet, viral infections, and pollution are all important etiological factors. Oral cancer is a disease of the poor and dispossessed, and reducing social inequalities requires national policies co-ordinated with wider health and social initiatives – the common risk factor approach: control of the environment; safe water; adequate food; public and professional education about early signs and symptoms; early diagnosis and intervention; evidence-based treatments appropriate to available resources; and thoughtful rehabilitation and palliative care. Reductions in inequalities, both within and between countries, are more likely to accrue from the application of existing knowledge in a whole-of-society approach. Basic research aimed at determining individual predisposition and acquired genetic determinants of carcinogenesis and tumor progression, thus allowing for targeted therapies, should be pursued opportunistically.
Peer Reviewed Yes
Published Yes
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Copyright Statement Copyright 2011 IADR/AADR. Published by Sage Publications. This is the author-manuscript version of the paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
Volume 23
Issue Number 2
Page from 237
Page to 246
ISSN 1544-0737
Date Accessioned 2012-03-08
Language en_US
Research Centre Menzies Health Institute Qld
Faculty Griffith Health Faculty
Subject Dentistry
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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