The genetics of alphaviruses

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Title The genetics of alphaviruses
Author Foo, Suan Sin; Chen, Weiqiang; Herrero, Lara; Bettadapura, Jayaram; Narayan, Jayasuryan; Dar, Lalit; Broor, Shobha; Mahalingam, Suresh
Journal Name Future Virology
Year Published 2011
Place of publication United Kingdom
Publisher Future Medicine
Abstract Alphaviruses are emerging human pathogens that are transmitted by arthropod vectors. Their ability to infect a wide range of vertebrate hosts including humans, equines, birds and rodents has brought about a series of epidemic and epizootic outbreaks worldwide. Their potential to cause a pandemic has spurred the interest of researchers globally, leading to the rapid advancement on the characterization of genetic determinants of alphaviruses. In this review, the focal point is placed on the genetics of alphaviruses, whereby the genetic composition, clinical features, evolution and adaptation of alphaviruses, modulation of IFN response by alphavirus proteins and therapeutic aspects of alphaviruses will be discussed.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.2217/fvl.11.123
Volume 6
Issue Number 12
Page from 1407
Page to 1422
ISSN 1746-0794
Date Accessioned 2012-03-30; 2012-04-23T21:50:05Z
Date Available 2012-04-23T21:50:05Z
Research Centre Institute for Glycomics
Faculty Faculty of Science, Environment, Engineering and Technology
Subject Virology
URI http://hdl.handle.net/10072/44603
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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