Solutions through Compounding: Terbinafine bilayer nail lacquer for onychomycosis
Author(s)
Haywood, Alison
Glass, Beverley
Griffith University Author(s)
Year published
2012
Metadata
Show full item recordAbstract
Onychomycosis, a term used to describe a fungal infection of the nail, presents a challenge to dermatologists because of the requirement for long courses of therapy and the high recurrence rates. This most common disease of the nails presents as tinea caused by dermatophytes such as Trichophyton rubrum and Trichophyton mentagrophytes var. interdigitale, although yeasts or non-dermatophytic moulds may also be causative organisms. Toenails are more commonly affected than fingernails, and these infections are frequently chronic and resistant to treatment.2 The infected nails appear discoloured, thickened and dystrophic, which ...
View more >Onychomycosis, a term used to describe a fungal infection of the nail, presents a challenge to dermatologists because of the requirement for long courses of therapy and the high recurrence rates. This most common disease of the nails presents as tinea caused by dermatophytes such as Trichophyton rubrum and Trichophyton mentagrophytes var. interdigitale, although yeasts or non-dermatophytic moulds may also be causative organisms. Toenails are more commonly affected than fingernails, and these infections are frequently chronic and resistant to treatment.2 The infected nails appear discoloured, thickened and dystrophic, which may impact negatively on the social life of the patient. The first stage of onychomycosis involves hyperkeratosis of the under surface of the distal nail plate and the distal nail bed (hyponychium). Progressive nail involvement produces total dystrophic onychomycosis (TDO) and destruction of the infected nail plate.
View less >
View more >Onychomycosis, a term used to describe a fungal infection of the nail, presents a challenge to dermatologists because of the requirement for long courses of therapy and the high recurrence rates. This most common disease of the nails presents as tinea caused by dermatophytes such as Trichophyton rubrum and Trichophyton mentagrophytes var. interdigitale, although yeasts or non-dermatophytic moulds may also be causative organisms. Toenails are more commonly affected than fingernails, and these infections are frequently chronic and resistant to treatment.2 The infected nails appear discoloured, thickened and dystrophic, which may impact negatively on the social life of the patient. The first stage of onychomycosis involves hyperkeratosis of the under surface of the distal nail plate and the distal nail bed (hyponychium). Progressive nail involvement produces total dystrophic onychomycosis (TDO) and destruction of the infected nail plate.
View less >
Journal Title
Australian Pharmacist
Volume
31
Issue
8
Publisher URI
Copyright Statement
Self-archiving of the author-manuscript version is not yet supported by this publisher. Please use the hypertext link above to access the journal's website or contact the author for more information.
Subject
Pharmaceutical Sciences
Pharmacology and Pharmaceutical Sciences