Synthesis of lactose-based S-linked sialylmimetics of alpha(2,3)-sialosides.
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| Title | Synthesis of lactose-based S-linked sialylmimetics of alpha(2,3)-sialosides. |
|---|---|
| Author | Liakatos, Angela; Kiefel, Milton; von Itzstein, Mark |
| Journal Name | Organic Letters |
| Editor | Amos B Smith, Carol Carr |
| Year Published | 2003 |
| Place of publication | Washington, DC |
| Publisher | American Chemical Society |
| Abstract | A new approach toward the synthesis of lactose-based S-linked sialylmimetics of α(2,3)-linked sialosides is described. These compounds, represented by the general structure 3, were prepared from methyl β-d-lactoside in 11 steps. It was found that the choice of protecting group was crucial to allow the efficient introduction of sulfur at the 3-position of the galactose ring. |
| Peer Reviewed | Yes |
| Published | Yes |
| Publisher URI | http://pubs.acs.org/journal/orlef7 |
| Alternative URI | http://dx.doi.org/10.1021/ol035733d |
| Copyright Statement | Copyright 2003 American Chemical Society. Self-archiving of the author-manuscript version is not yet supported by this publisher. Please refer to the journal link for access to the definitive, published version or contact the author for more information. |
| Volume | 5 |
| Issue Number | 23 |
| Page from | 4365 |
| Page to | 4368 |
| ISSN | 1523-7060 |
| Date Accessioned | 2004-03-19 |
| Date Available | 2009-10-19T05:23:48Z |
| Language | en_AU |
| Research Centre | Institute for Glycomics |
| Faculty | Institute for Glycomics |
| Subject | PRE2009-Organic Chemical Synthesis |
| URI | http://hdl.handle.net/10072/5841 |
| Publication Type | Journal Articles (Refereed Article) |
| Publication Type Code | c1 |
Please use this identifier to cite this record: http://hdl.handle.net/10072/5841
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