Titanate–silica mesostructured nanocables: synthesis, structural analysis and biomedical applications
Author(s)
Su, Yonghua
Qiao, Shizhang
Yang, Huagui
Yang, Chen
Jin, Yonggang
Stahr, Frances
Sheng, Jiayu
Cheng, Lina
Ling, Changquan
Lu, Gao Qing
Griffith University Author(s)
Year published
2010
Metadata
Show full item recordAbstract
1D hierarchical composite mesostructures of titanate and silica were synthesized via an interfacial surfactant templating approach. Such mesostructures have complex core–shell architectures consisting of single-crystalline H2Ti3O7 nanobelts inside the ordered mesoporous SiO2 shell, which are nontoxic and highly biocompatible. The overall diameter of as-prepared 1D hierarchical composite mesostructures is only approx. 34.2 nm with a length over 500 nm on average. A model to explain the formation mechanism of these mesostructures has been proposed; the negatively charged surface of H2Ti3O7 nanobelts controls the formation of ...
View more >1D hierarchical composite mesostructures of titanate and silica were synthesized via an interfacial surfactant templating approach. Such mesostructures have complex core–shell architectures consisting of single-crystalline H2Ti3O7 nanobelts inside the ordered mesoporous SiO2 shell, which are nontoxic and highly biocompatible. The overall diameter of as-prepared 1D hierarchical composite mesostructures is only approx. 34.2 nm with a length over 500 nm on average. A model to explain the formation mechanism of these mesostructures has been proposed; the negatively charged surface of H2Ti3O7 nanobelts controls the formation of the octadecyltrimethylammonium bromide (C18TAB) bilayer, which in turn regulates the cooperative self-assembly of silica and C18TAB complex micelles on the interface to produce a mesoporous silica shell. More importantly, the application of synthesized mesostructured nanocables as anticancer drug reservoirs has also been explored, which indicates that the membranes containing these mesoporous nanocables have a great potential to be used as transdermal drug delivery systems.
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View more >1D hierarchical composite mesostructures of titanate and silica were synthesized via an interfacial surfactant templating approach. Such mesostructures have complex core–shell architectures consisting of single-crystalline H2Ti3O7 nanobelts inside the ordered mesoporous SiO2 shell, which are nontoxic and highly biocompatible. The overall diameter of as-prepared 1D hierarchical composite mesostructures is only approx. 34.2 nm with a length over 500 nm on average. A model to explain the formation mechanism of these mesostructures has been proposed; the negatively charged surface of H2Ti3O7 nanobelts controls the formation of the octadecyltrimethylammonium bromide (C18TAB) bilayer, which in turn regulates the cooperative self-assembly of silica and C18TAB complex micelles on the interface to produce a mesoporous silica shell. More importantly, the application of synthesized mesostructured nanocables as anticancer drug reservoirs has also been explored, which indicates that the membranes containing these mesoporous nanocables have a great potential to be used as transdermal drug delivery systems.
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Journal Title
Nanotechnology
Volume
21
Subject
Inorganic chemistry not elsewhere classified
Biomedical engineering not elsewhere classified