Engineering microfluidic concentration gradient generators for biological applications
View/ Open
Author(s)
Toh, Alicia GG
Wang, ZP
Yang, Chun
Nam-Trung, Nguyen
Griffith University Author(s)
Year published
2014
Metadata
Show full item recordAbstract
This paper reviews the latest developments in the design and fabrication of concentration gradient generators for microfluidics-based biological applications. New gradient generator designs and their underlying mass transport principles are discussed. The review provides a blueprint for design considerations of concentration gradients in different applications, specifically biological studies. The paper discusses the basic phenomena associated with microfluidic gradient generation and the different gradient generation modes used in static and dynamic biological assays. Finally, the paper summarizes all factors to consider ...
View more >This paper reviews the latest developments in the design and fabrication of concentration gradient generators for microfluidics-based biological applications. New gradient generator designs and their underlying mass transport principles are discussed. The review provides a blueprint for design considerations of concentration gradients in different applications, specifically biological studies. The paper discusses the basic phenomena associated with microfluidic gradient generation and the different gradient generation modes used in static and dynamic biological assays. Finally, the paper summarizes all factors to consider when using concentration gradient generators and puts forward perspectives on the future development of these devices.
View less >
View more >This paper reviews the latest developments in the design and fabrication of concentration gradient generators for microfluidics-based biological applications. New gradient generator designs and their underlying mass transport principles are discussed. The review provides a blueprint for design considerations of concentration gradients in different applications, specifically biological studies. The paper discusses the basic phenomena associated with microfluidic gradient generation and the different gradient generation modes used in static and dynamic biological assays. Finally, the paper summarizes all factors to consider when using concentration gradient generators and puts forward perspectives on the future development of these devices.
View less >
Journal Title
Microfluidics and Nanofluidics
Volume
16
Issue
1-2
Copyright Statement
© 2014 Springer Berlin Heidelberg. This is an electronic version of an article published in Microfluidics and Nanofluidics, Vol. 16(1-2), pp. 1-18, 2014. Microfluidics and Nanofluidics is available online at: http://link.springer.com/ with the open URL of your article.
Subject
Mechanical engineering
Engineering practice and education not elsewhere classified
Nanotechnology
Nanoelectromechanical systems