Isolation and Structure of Some Constituents of the Australian Medicinal Plant, Tinospora smilacina (“Snakevine”).
Author(s)
Hungerford, Natasha Lynn
Sands, Donald P. A.
Kitching, William
Griffith University Author(s)
Year published
1998
Metadata
Show full item recordAbstract
The structures of a number of compounds isolated from the stems of Tinospora smilacina (known as ‘snakevine’) have been determined. The known clerodane-type compound columbin is a major component, and two new minor compounds incorporate a heavily oxygenated tetrahydrofuran ring in place of the furan ring of columbin. The lignan isolariciresinol is also shown to be a minor component, along with dihydrosyringenin. The traditional medicinal use of the vine, particularly in countering snake venom, may be associated primarily with the presence of columbin.The structures of a number of compounds isolated from the stems of Tinospora smilacina (known as ‘snakevine’) have been determined. The known clerodane-type compound columbin is a major component, and two new minor compounds incorporate a heavily oxygenated tetrahydrofuran ring in place of the furan ring of columbin. The lignan isolariciresinol is also shown to be a minor component, along with dihydrosyringenin. The traditional medicinal use of the vine, particularly in countering snake venom, may be associated primarily with the presence of columbin.
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Journal Title
Australian Journal of Chemistry
Volume
51
Subject
Natural Products Chemistry
Chemical Sciences