Antiserum raised against the Epstein-Barr virus BARF0 protein reacts to HLA-DRb chain

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Title Antiserum raised against the Epstein-Barr virus BARF0 protein reacts to HLA-DRb chain
Author Schroder, Wayne Ashley; Kienzle, N.; Bushell, Gillian Robin; Sculley, T
Journal Name Archives of Virology
Year Published 2002
Place of publication SACHSENPLATZ 4-6,PO
Publisher SPRINGER-VERLAG WIEN,
Abstract The role that Epstein-Barr virus plays in nasopharyngeal carcinoma and Burkitt's lymphoma has been under intense study for many years. With only a limited set of viral genes being expressed in these tumours it has been difficult to understand how the virus could cause/aid in the generation of the tumours. In 1997 a paper was published by Fries et al. [Fries et al. (1997) Identification of a novel protein encoded by the BamHI A region of the Epstein-Barr virus. J Virol 71: 2765–2771.] in which a rabbit serum was generated and used to identify protein products (RK-BARF0) encoded from the BamH1 A region of EBV. In this paper we have isolated these proteins from two-dimensional gels and identified them, using mass spectrometry, as components of HLA DR.
Peer Reviewed Yes
Published Yes
Alternative URI http://dx.doi.org/10.1007/s007050200021
Volume 147
Issue Number 4
Page from 723
Page to 729
ISSN 0304-8608
Date Accessioned 2003-04-15
Date Available 2010-07-28T06:59:26Z
Language en_AU
Research Centre Griffith Medical Research College
Faculty Faculty of Science
Subject PRE2009-Medical Virology
URI http://hdl.handle.net/10072/6968
Publication Type Journal Articles (Refereed Article)
Publication Type Code c1

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